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Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders

Identifieur interne : 005B34 ( Main/Exploration ); précédent : 005B33; suivant : 005B35

Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders

Auteurs : H. M. Ögmundsd Ttir [Islande] ; H. Hilmarsd Ttir ; J. Björnsson [Islande] ; W. P. Holbrook [Islande]

Source :

Journal of Oral Pathology & Medicine [ 0904-2512 ] ; 2009-10.

RBID : ISTEX:35B20F911B24DFFD8A395986A2F4BF722433D316

English descriptors

KwdEn :
- Allelic imbalance, Biopsy, Buccal, Candida, Carcinoma, Cell carcinoma, Clin, Clin path, Clinical diagnosis, Clinical outcome, Clinical pathology, Desquamative gingivitis, Dysplasia, Exon, Extensive leukoplakia, Genomic instability, Hard palate, Histopathological diagnosis, Hotspot, Hspc, Hyperkeratosis, Hyperpl, Hyperplasia, Lateral borders, Lesion, Leukoplakia, Lichen, Lichen planus, Malignancy, Malignant, Mucosal, Mucosal lesions, Mutation, Mutation analysis, Oncol, Oral cancer, Oral lesions, Oral lichen planus, Oral mucosa, Oral oncol, Oral pathol, Oscc, Pathol, Planus, Poor prognosis, Previous study, Progression, Several occasions, White patches.
Teeft :
- Allelic imbalance, Biopsy, Buccal, Candida, Carcinoma, Cell carcinoma, Clin, Clin path, Clinical diagnosis, Clinical outcome, Clinical pathology, Desquamative gingivitis, Dysplasia, Exon, Extensive leukoplakia, Genomic instability, Hard palate, Histopathological diagnosis, Hotspot, Hspc, Hyperkeratosis, Hyperpl, Hyperplasia, Lateral borders, Lesion, Leukoplakia, Lichen, Lichen planus, Malignancy, Malignant, Mucosal, Mucosal lesions, Mutation, Mutation analysis, Oncol, Oral cancer, Oral lesions, Oral lichen planus, Oral mucosa, Oral oncol, Oral pathol, Oscc, Pathol, Planus, Poor prognosis, Previous study, Progression, Several occasions, White patches.

Abstract

Objectives: In a previous cross‐sectional study, the authors found a higher rate of TP53 mutation in oral lichen planus (OLP) than in hyperkeratosis. By analysing for TP53 mutations in serial samples from patients on long‐term follow‐up of their oral lesions, it was hoped to determine if these mutations were related to disease progression.

Url:

https://api.istex.fr/document/35B20F911B24DFFD8A395986A2F4BF722433D316/fulltext/pdf

DOI: 10.1111/j.1600-0714.2009.00767.x

Affiliations:

Islande

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Le document en format XML

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<term>Carcinoma</term>
<term>Cell carcinoma</term>
<term>Clin</term>
<term>Clin path</term>
<term>Clinical diagnosis</term>
<term>Clinical outcome</term>
<term>Clinical pathology</term>
<term>Desquamative gingivitis</term>
<term>Dysplasia</term>
<term>Exon</term>
<term>Extensive leukoplakia</term>
<term>Genomic instability</term>
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<term>Histopathological diagnosis</term>
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<term>Poor prognosis</term>
<term>Previous study</term>
<term>Progression</term>
<term>Several occasions</term>
<term>White patches</term>
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<term>Clinical outcome</term>
<term>Clinical pathology</term>
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<term>Dysplasia</term>
<term>Exon</term>
<term>Extensive leukoplakia</term>
<term>Genomic instability</term>
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<term>Histopathological diagnosis</term>
<term>Hotspot</term>
<term>Hspc</term>
<term>Hyperkeratosis</term>
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<front><div type="abstract">Objectives:  In a previous cross‐sectional study, the authors found a higher rate of TP53 mutation in oral lichen planus (OLP) than in hyperkeratosis. By analysing for TP53 mutations in serial samples from patients on long‐term follow‐up of their oral lesions, it was hoped to determine if these mutations were related to disease progression.</div>
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Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders

Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri